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. 2007 Nov 21;2(11):e1226. doi: 10.1371/journal.pone.0001226

Table 1. Characteristics of NSCLC Cell Lines.

Cell Line EGFR Gefitinib IC50 Ras
H1299 WT 38.0 µM N-RasQ61K
H1819 WT 4.7 µM WT
H460 WT 8.0 µM K-RasQ61H
H1975 L858R, T790M 1.9 µM WT
HCC2279 Δ746–750 5.0 µM WT
H3255 L858R 9.0 nM WT
H4006 Δ746–750 30.0 nM WT
HCC827 Δ746–750 16.0 nM WT

Abbreviations: WT, wild-type; IC50 , 50% inhibitory concentration Gefitinib IC50 values have been reported (Fujimoto et al., 2005).