TABLE 3.

Infectious diseases, allergies and risk of neuroblastoma (children older than one year)

	Cases		Controls		OR*	95% CI*
	N°	%	N°	%
Infectious diseases
Selected childhood infections†
Yes vs no	57	17	72	24	0.60	0.39–0.93
0	273	83	231	76	1.00	reference
1	55	17	64	21	0.66	0.42–1.02
2+	2	0.6	9	3	0.13	0.02–0.65
Ear infections
Yes vs no	254	80	210	69	1.76	1.20–2.58
0	65	20	95	31	1.00	reference
< 1 per month	190	61	167	55	1.62	1.09–2.41
≥ 1 per month	55	18	39	13	2.13	1.24–3.66
Other infections‡
Yes vs no	39	12	29	9	1.26	0.74–2.11
Allergies
Asthma	18	5	25	8	0.69	0.36–1.34
Hay fever	8	2	17	6	0.43	0.18–1.04
Eczema	19	6	21	7	0.82	0.41–1.62
Any allergy§	45	14	58	19	0.68	0.44–1.07

^*Unmatched odds ratios (OR) adjusted for child’s diagnosis reference age, mother’s race, mother’s education and household income at birth year, CI: confidence interval.

^†Selected childhood infections included chickenpox, mumps, German measles and red measles.

^‡Other infection included upper and lower respiratory tract, digestive and kidney infection (ear infection excluded).

^§Any allergy included asthma, hay fever, other ear throat nose allergiy as rhinitis and sinusitis, eczema, and other dermatological allergy as urticaria, contact dermatitis, food dermatitis and hypersensitivity to drugs.