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(A) Loss of cyp26a1 expression in cranial mesoderm in DEAB-treated embryos and lack of induction by a DMSO-soaked bead.
(B) Induction of cyp26a1 expression by an RA bead; inset, optical section showing cyp26a1 induction in both the neural tube (nt), lying above the notochord (n), and lateral mesoderm (white arrowhead). The asterisk (*) indicates the bead.
(C) Weak induction of cyp26b1 (black arrowhead).
(D) No induction of cyp26c1.
