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. Author manuscript; available in PMC: 2008 Nov 1.
Published in final edited form as: Hear Res. 2007 Jul 19;233(1-2):46–53. doi: 10.1016/j.heares.2007.07.003

Table 1.

Kinetics of hair cell loss for variable cisplatin doses. T 1/2 represents the time in hours required to achieve 50% hair cell loss based on linear regression analysis. The rate of hair cell loss once hair cell loss was initiated was determined by linear regression of data points from Figure 5 and is shown as the slope of hair cell loss versus time, or the percent hair cell loss per hour (r2).

Cisplatin concentration t1/2 % Total hair cells lost / hr (r2)
50 μM 11.6 hrs 9%/hr (0.84)
100 μM 9.6 hrs 9%/hr (0.90)
250 μM 8.5 hrs 11%/hr (0.67)
500 μM 5.6 hrs 18%/hr (0.83)
1000 μM 5.1 hrs 16%/hr (0.89)