Figure 5. Interplay between GSH transport at the basolateral plasma and inner mitochondrial membranes in renal proximal tubule.

This summary scheme illustrates the interplay between various carriers that may function either directly or indirectly in the transport of GSH across the basolateral plasma membrane (BLM) and the inner mitochondrial membrane (IMM). Thick arrows indicate flux of substrate between pathways. See text for discussion. Abbreviations: DIC, dicarboxylate carrier; NaC2, sodium-dicarboxylate carrier 2; Oat3, organic anion transporter 3; 2-OG, 2-oxoglutarate; OGC, 2-oxoglutarate carrier; P_i²⁻, inorganic phosphate