Table 3.

Large gene families in T. vaginalis. Only gene families, or aggregates of gene families mediating a given process, for which there are more than 30 members and that have been assigned a putative function are listed. (See SOM text for subfamily organization.) The small guano-sine triphosphatases (GTPases) are the sum of Rab and ARF small GTPases only; all other GTPases are shown in table S12. ABC, ATP-binding cassette; MFS, major facilitator superfamily; MOP, multi-drug/oligosaccharidyl-lipid/polysaccharide; AAAP, amino acid/auxin permease.

Gene family (functional unit)	Members
Protein kinases	927
BspA-like gene family	658
Membrane trafficking: small GTPases	328
rDNA gene cluster	~250
Cysteine peptidase (clan CA, family C19)	117
Membrane trafficking: vesicle formation	113
ABC transporter superfamily	88
GP63-like (leishmanolysin)	77
MFS transporter family	57
MOP flippase transporter family	47
Cysteine peptidase (clan CA, family C1)	48
AAAP transporter family	40
Dynein heavy chain	35
P-ATPase transporter family	33
Serine peptidase (clan SB, family S8)	33
Membrane trafficking: vesicle fusion	31