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. Author manuscript; available in PMC: 2008 Nov 23.
Published in final edited form as: Biochem Biophys Res Commun. 2007 Sep 14;363(3):495–499. doi: 10.1016/j.bbrc.2007.08.192

Figure 1. Enhancement of HIV-1 infection by a non-signaling CD147 mutant.

Figure 1

A. Analysis of CD147 expression on stable clones of CD147wt and CD147.PG180,181AA-transfected CHO cells by flow cytometry. Cells were stained with FITC-conjugated anti-CD147 mAb, and analyzed on BD FACScan. B. Analysis of HIV-1 replication by luciferase activity. Stable clones of CHO cells transfected with wild-type (CHO.CD147wt) or non-signaling CD147 (CHO.CD147PG180,181AA) or with an empty vector pcDNA3.1 (CHO.pcDNA) were inoculated with luciferase-expressing HIV-1 pseudotyped with an envelope of amphotropic murine leukemia virus (MuLV). Luciferase expression was measured on day 4 post-infection. Results and presented as mean ± SE of three independent wells.