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Flow cytometric analysis of splenic and peritoneal cells. In C1q-deficient mice there was a reduction of (A) marginal zone B cells (percentage of CD21highCD23low, CD19+ gated splenic B cells) and this was associated with an increase of (B) plasma cells (percentage of CD138+, B220−CD90− gated splenic cells). Each symbol represents one mouse; VH3H9R/VLκ8R.MRL/Mp mice (diamonds) and VH3H9R.MRL/Mp mice (triangles); C1q-deficient mice are represented with open symbols.
