Table 2 Adjusted regression coefficients (with 95% confidence intervals) for association between inflammatory markers and FEV₁ % predicted in participants with and without obstructive lung disease (OLD).

Variable	β with 95% confidence intervals*		p value†
	With OLD	Without OLD
IL‐6	−5.3 (−9.1 to −1.5)	−3.1 (−4.3 to −1.9)	0.09
TNF	3.6 (−1.8 to 9)	−1.9 (−3.7 to 0.1)	0.03
CRP	−2.2 (−4.8 to 0.4)	−2 (−3 to −1)	0.6

IL‐6, interleukin 6; TNF, tumour necrosis factor; CRP, C‐reactive protein.

*Regression coefficients (β) denote the estimated difference in FEV₁ % predicted associated with an increase of one log unit in individual inflammatory markers. β adjusted for age, race, sex, site, smoking status (current smokers, ever smoked versus never smoked), pack years of smoking, body mass index (>30 and <20 kg/m²), history of congestive heart failure, diabetes, and oral steroid use.

†p value for interaction between obstructive lung disease and the association between FEV₁ and inflammatory marker.