Table 3 Asthma and hay fever according to HRT use in 2206 women aged 46–54 years.

	No HRT (n = 1666) (%)	HRT (n = 540) (%)	OR (95% CI)*	p value
Asthma†	7.2	10.0	1.50 (1.03 to 2.20)	0.035
Wheeze‡	18.7	23.1	1.54 (1.17 to 2.02)	0.002
Three or more symptoms§	13.3	18.5	1.62 (1.20 to 2.20)	0.002
Night symptoms**	14.2	11.8	0.85 (0.61 to 1.18)	0.3
Hay fever††	23.0	27.4	1.47 (1.14 to 1.88)	0.003
Allergic asthma‡‡	3.9	5.8	1.77 (1.09 to 2.89)	0.022

*From logistic regression models with adjustment for smoking habits, BMI, age, centre, and social class.

†Asthma medication and/or asthma attacks in the last 12 months.

‡Wheeze in the last 12 months.

§Symptoms included: wheeze, wheeze with shortness of breath, wheeze without cold, waking with tightness in chest, waking with shortness of breath, waking with cough, asthma attacks, current asthma medication.

**Waking with tightness in chest or waking with shortness of breath.

††Hay fever or nasal allergies.

‡‡Asthma and hay fever.