Table 4 Asthma and hay fever in women according to HRT use stratified by BMI in tertiles.
| No HRT (%) | HRT (%) | OR (95% CI)* | p value | |
|---|---|---|---|---|
| Lower tertile BMI <22.76 (n = 716) | ||||
| Asthma† | 5.3 | 12.0 | 2.28 (1.18 to 4.40)** | 0.014 |
| Wheeze‡ | 14.9 | 25.8 | 1.85 (1.16 to 2.96)†† | 0.010 |
| Hay fever§ | 20.7 | 29.7 | 2.06 (1.33 to 3.19)‡‡ | 0.001 |
| Medium tertile BMI 22.76–25.71 (n = 736) | ||||
| Asthma† | 5.6 | 6.3 | 1.28 (0.61 to 2.71)** | 0.513 |
| Wheeze‡ | 15.0 | 19.7 | 1.56 (0.95 to 2.54)†† | 0.076 |
| Hay fever§ | 23.1 | 25.3 | 1.20 (0.79 to 1.84)‡‡ | 0.395 |
| Upper tertile BMI >25.71 (n = 709) | ||||
| Asthma† | 10.6 | 12.4 | 1.31 (0.71 to 2.42)** | 0.382 |
| Wheeze‡ | 24.1 | 26.7 | 1.28 (0.80 to 2.06)†† | 0.302 |
| Hay fever§ | 25.0 | 26.9 | 1.39 (0.89 to 2.17)‡‡ | 0.153 |
*From logistic regression models with adjustment for smoking habits, BMI (within tertile), age, centre, and type of dwelling (as a proxy for social class).
†Asthma medication and/or asthma attacks in the last 12 months.
‡Wheeze in the last 12 months.
§Hay fever or nasal allergies.
**Interaction in effect of HRT on asthma between lean and normal/overweight women pinteraction = 0.020.
††Interaction in effect of HRT on wheeze between lean and normal/overweight women pinteraction = 0.026.
‡‡Interaction in effect of HRT on hay fever between lean and normal/overweight women pinteraction = 0.076.