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Maximum intensity projections showing cell orientation for the three models (UN, PC, CO) within the two different zones (A-zone and D-zone). The long axis of the construct is horizontal. (A, C, E) Randomly oriented cells within the D-zone for all three models. (B, D, F) Cells within the A-zone. Note that cells in the UN model are randomly oriented (B), whereas cells within the PC and CO models (D, F) are aligned parallel to the long axis of the construct.
