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. Author manuscript; available in PMC: 2008 Sep 22.
Published in final edited form as: Life Sci. 2007 Sep 9;81(15):1223–1227. doi: 10.1016/j.lfs.2007.08.031

Figure 1.

Figure 1

Schematic illustration of the experimental protocol. Mice were subjected to 30 min coronary artery occlusion and 2 h of reperfusion. No intervention was performed in Control animals (n = 9). Hearts underwent postconditioning (PostC) in early reperfusion periods. Ischemic PostC (R/I) was elicited by three cycles of 20 s reperfusion and ischemia before 2 h of reperfusion (n = 8). Isoflurane (ISO, n = 8) or SNC-121 (SNC, n = 8) was administered for 5 min, beginning at 3 min before and ending 2 min after reperfusion. Groups were treated with 2-mercaptopropionyl glycine (MPG) before reperfusion (Pre MPG, MPG + R/I, MPG + ISO, and MPG + SNC, n = 8), or after reperfusion (Post MPG, R/I + MPG, ISO + MPG, and SNC + MPG, n = 8).