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. Author manuscript; available in PMC: 2007 Nov 19.
Published in final edited form as: Insect Biochem Mol Biol. 2005 Nov 8;36(1):37–46. doi: 10.1016/j.ibmb.2005.10.004

Table 1.

Kinetic constants for inhibition of a panel of serine proteinase by Nec-fl and Nec-ΔN*

Proteinase Nec-fl
 Nec-ΔN
  ka (M−1 s−1) SI (inhibitor/proteinase) ka (M−1 s−1) SI (inhibitor/proteinase)
Human neutrophile elastase 1.8 × 105 1.1 1.5 × 105 1.6
Porcine pancreatic elastase 1.7 × 104 9.0 2.2 × 105 1.8
Chymotrypsin 4.6 × 104 3.9 4.0 × 104 3.1
Thrombin 1.9 × 10² >100 1.2 × 10² >100
Trypsin Undetectable Infinity Undetectable Infinity
Cathepsin G 5.3 × 105 1.1 3.2 × 105 1.1
*

Errors for the analysis of the kinetic parameters are 10%. The results represent the mean of, at least, three independent experiments.