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. Author manuscript; available in PMC: 2007 Nov 19.
Published in final edited form as: J Biol Chem. 2003 Jul 24;278(41):39461–39469. doi: 10.1074/jbc.M306111200

FIG. 4. Western blot analysis of mediators of apoptosis.

FIG. 4

a, A375 cells were pre-treated with NO-Cbl for 16 h, followed by Apo2L/TRAIL for 6 or 12 h, which resulted in cleavage of caspase-3, caspase-8, and PARP. b, sequential NO-Cbl and Apo2L/TRAIL treatment caused cleavage of XIAP but not cIAP-1 or FLIP.