Figure 5.

Significant changes in transcript levels of panels of genes responding to the treatment of HLE cells responding to the 50-μM H₂O₂ treatment for 1 hour (Fig. 4). Diagram represents of distribution of normalized signal intensities of tested versus common reference (pooled) samples. The genes included were only the 1171 that met the SAM criteria for significance of up- or downregulation. Top: human lens epithelial cells treated with 50 μM H₂O₂ (H₂O₂/serum pathway). Middle: cells treated with 50 μM H₂O₂ followed by 1 hour of serum starvation, (H₂O₂ pathway). Bottom: control cells (H₂O/serum pathway). Triplicates are shown.