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. Author manuscript; available in PMC: 2007 Nov 19.
Published in final edited form as: Adv Enzyme Regul. 2007 Mar 1;47:27–40. doi: 10.1016/j.advenzreg.2006.12.007

Fig. 1.

Fig. 1

Sec14p regulates both PtdCho and phosphoinositide biosynthesis. Sec14p coordinates the interface between lipid metabolism and transport vesicle biogenesis from yeast trans-Golgi membranes. Sec14p-mediated regulation of lipid metabolism is twofold: inhibition of PtdCho biosynthesis and diacylglycerol (DAG) consumption via the CDP-choline pathway (left panel) and stimulation of PtdIns-4-phosphate production via the Pik1p PtdIns 4-OH kinase.