Skip to main content
. Author manuscript; available in PMC: 2008 Sep 1.
Published in final edited form as: J Autoimmun. 2007 Aug 9;29(2-3):125–133. doi: 10.1016/j.jaut.2007.06.001

Figure 5.

Figure 5

Frequency of λ1+ marginal zone B cells in VH3H9/56R-KI/IL-2 KO mice. The frequency of marginal zone (MZ – CD21hiCD23lo) and follicular (FO – CD21intCD23+)B cells was determined by flow cytometric expression of CD21 and CD23 on CD19+λ1+ or CD19+λ1− splenocytes isolated from VH3H9/56R-KI/IL-2 WT or VH3H9/56R-KI/IL-2 KO mice. Results shown are from a single representative experiment. Isotype controls were negative. The frequency of marginal zone CD19λ1+ B cells was greater in VH3H9/IL-2 KO (n=10) as compared to VH3H9/IL-2 WT (n=14) mice (p=0.0005). Marginal zone CD19λ1− B cells were also statistically different between these mice (p=0.03).