Table 1.

The grading system used for late genitourinary radiation side effects.

Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Nocturia twice baseline. Microscopic hematuria. Light mucosal atrophy and minor telangiectasia.	Moderate frequency. Nocturia more than twice baseline. Generalized telangiectasia. Intermittent macroscopic hematuria. Two or fewer blood transfusions. Two or fewer coagulations. Regular non- narcotic or occasional narcotic for pain.	Severe frequency and dysuria. Nocturia more frequent than once every hour. Reduction in bladder capacity (150 cc). Frequent hematuria. More than two transfusions. More than one coagulation for hematuria. Regular narcotic for pain.	Severe hemorrhagic cystitis. Ulceration. Requirement for urinary diversion and/or cystectomy.	Fatal toxicity