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. 2007 Dec 1;21(23):3085–3094. doi: 10.1101/gad.1609007

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Copyright © 2007, Cold Spring Harbor Laboratory Press

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Figure 3. — Analysis of hRad51-ssDNA filament disruption by BLM using electron microscopy. (A) The hRad51-ssDNA filament (indicated by arrows) was formed and then mixed with hRPA. hRad51-ssDNA filament formed in the absence of hRPA is shown in the bottom left corner. (B) hRPA–ssDNA complexes (in the encircled area) are indicated by arrows. (C) The hRad51-ssDNA filament was formed and then mixed with BLM and hRPA. The reaction resulted in disruption of the filament and formation of hRPA–ssDNA complexes (indicated by arrows). Bar, 50 nm.