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Wheel running consolidates sleep/wake behavior during the dark period, especially in WT mice. Wheel running in WT mice produces more wakefulness during the dark period, and wakefulness occurs in considerably longer bouts. A similar pattern occurs in orexin KO mice, though the increase in wake bout duration is smaller. Additionally, wheel running doubles the number of cataplexy episodes in orexin KO mice. *P < 0.05; **P < 0.01.
