Fig. 5. True hypoxia leads to early activation of IK1.
A. Representative Ba2+-sensitive current traces recorded in a WT myocyte before and after a 4 min application of nominally O2-free solution (N2) at 28 °C. The current activated by hypoxia displays strong inward rectification, confirming it is IK1. B. At −60 mV the Ba2+-sensitive current is increased by 60% when compared to control (n=4, p<0.05).
