Insulin at a dose of 10 IU/mL significantly decreased the gene expression of hepatic TNF at 12 and 24 h, hepatic IL-1βmRNA expression 12 h, hepatic IL-6 mRNA at 12 h, hepatic IL-10 mRNA at 8 and 12 h, and hepatic IFN-γmRNA at 12 and 24 h after LPS administration. *Significant difference between LPS and LPS plus insulin, P < 0.05.