. 2007 Oct 16;87(1):1–10. doi: 10.1007/s00277-007-0403-6

Table 1.

Chromosomal and molecular markers in CMPD [8, 9, 22, 23, 52, 69]

	Karyotype abnormalities	Molecular markers	Molecular MRD markers
CML	t(9;22)(q34;q11), in all cases BCR–ABL	BCR/ABL	+
PV	In some cases: +8, +9, del(20q), del(13q), del(1p)	JAK2V617F	+
PV	In some cases: +8, +9, del(20q), del(13q), del(1p)	JAK2 exon 12 in V617F-negative cases	+
CIMF	In some cases: del(13q), del(20q), +8, +9, partial trisomy 1q	JAK2V617F	+
CIMF		MPLW515	+
ET	In rare cases +8, +9, del(13q),	JAK2V617F	+
ET	In rare cases +8, +9, del(13q),	MPLW515	+
CMPD-U	In some cases +8, +9, del(20q)	JAK2V617F	+
CMPD-U	In rare cases 8p11 translocations	FGFR1 rearrangements	+
CEL/HES	in some cases: +8, i(17q),	PDGFRA/FIP1L1 in CEL	+
CNL	in some cases: +8, +9, del(20q)	−	−
CMML	−7, +8, del(20q)	NRAS in some cases	+