Table 3 Sensitivity, specificity, and positive and negative predictive value (PPV and NPV) of variables for the identification of patients who were listed for liver transplantation (n = 8) following paracetamol hepatotoxicity.
| Sensitivity % | Specificity % | PPV % | NPV % | |
|---|---|---|---|---|
| Encephalopathy >grade III | 100 (69–100) | 100 (92–100) | 100 (69–100) | 100 (92–100) |
| pH <7.3 | 75 (35–97) | 93 (77–99) | 75 (35–97) | 93 (77–99) |
| PT >100 seconds | 88 (47–100) | 92 (78–98) | 70 (35–93) | 97 (85–100) |
| Creatinine >300 μmol/l | 50 (16–84) | 97 (86–100) | 80 (28–99) | 90 (76–97) |
| Creatinine >200 μmol/l | 88 (47–100) | 92 (78–98) | 70 (35–93) | 97 (85–100) |
| Serum bilirubin >90 μmol/l | 88 (47–100) | 78 (62–90) | 47 (21–73) | 97 (82–100) |
| Glucose <2.6 mmol/l | 62 (24–91) | 97 (85–100) | 83 (36–100) | 92 (78–98) |
Total n = 45.
95% CI in parentheses.