Table 4 Clinical utility of the children's head injury algorithm for the prediction of important clinical events rule.
| No clinically significant head injury | Clinically significant head injury | Total | |
|---|---|---|---|
| CHALICE negative | 19 558 | 4 | 19 562 |
| CHALICE positive | 2 933 | 277 | 3 210 |
| Total | 22 491 | 281 | 22 772 |
| Sensitivity | 98.6% | (96.4% to 99.6%) | |
| Specificity | 86.9% | (86.5% to 87.4%) | |
| Positive predictive value | 8.63% | (7.68% to 9.65%) | |
| Negative predictive value | 99.9% | (99.9% to 100%) | |
| CT ordering rate | 14.1% | (13.6% to 14.6%) | |
| Performance of CHALICE rule for patients with GCS 13–15 | |||
| No significant intracranial pathology | Significant intracranial pathology | Total | |
|---|---|---|---|
| CHALICE negative | 19 558 | 4 | 19 562 |
| CHALICE positive | 2 853 | 164 | 3 017 |
| Total | 22 411 | 168 | 22 579 |
| Sensitivity | 97.6% | (94.0% to 99.4%) | |
| Specificity | 87.3% | (86.8% to 87.7%) | |
| Positive predictive value | 5.44% | (4.65% to 6.31%) | |
| Negative predictive value | 99.9% | (99.9% to 100%) | |
| CT ordering rate | 13.3% | (12.9% to 13.8%) | |
| Performance of CHALICE rule for prediction of neurosurgical intervention | |||
| No neurosurgical intervention | Neurosurgical intervention | Total | |
|---|---|---|---|
| CHALICE negative | 19 559 | 3 | 19 562 |
| CHALICE positive | 3 076 | 134 | 3 210 |
| Total | 22 635 | 137 | 22 772 |
| Sensitivity | 97.8% | (93.7% to 99.6%) | |
| Specificity | 86.4% | (86.0% to 86.9%) |
CHALICE, children's head injury algorithm for the prediction of important clinical events; CT, computed tomography; GCS, Glasgow Coma Score.
Values in parentheses are 95% CI.