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. Author manuscript; available in PMC: 2007 Nov 21.
Published in final edited form as: Cancer Res. 2007 Mar 1;67(5):2015–2021. doi: 10.1158/0008-5472.CAN-06-3617

Figure 1.

Figure 1

UVB-induced apoptosis in mouse skin. A, apoptotic cells in WT and COX-2−/− mice were detected by TUNEL assay at 24 h following 5.0 kJ/m2 UVB exposure. Columns, mean (n = 4 mice per group) of the % TUNEL-positive cells per 100 basal cells; bars, SD. *, P < 0.01. B, mice were sacrificed 24 h after 5.0 kJ/m2 UVB irradiation, and isolated protein extracts (50 μg) were electrophoresed, transferred to a polyvinylidene difluoride membrane, and the membranes probed using antibodies for COX-2 and COX-1. Each lane represents an individual mouse.