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. Author manuscript; available in PMC: 2008 Oct 11.
Published in final edited form as: Cell Host Microbe. 2007 Oct 11;2(4):240–249. doi: 10.1016/j.chom.2007.09.001

Figure 5.

Figure 5

Growth and plaque size of a virus expressing the 1918 PB1-F2. An otherwise isogenic virus engineered to express the PB1-F2 protein from the 1918 pandemic strain (1918) was compared to the wt PR8 strain (WT). (A) HA titer is compared for a virus expressing the 1918 PB1-F2 to wt PR8. Error bars indicate standard deviation of the measurements and an asterisk (*) indicates a significant difference at that timepoint by the paired Student’s t-test (p < 0.05). (B) Plaque size was measured for a virus expressing the 1918 PB1-F2 (1918) compared to wt PR8 (WT) and a virus that does not express the PB1-F2 protein (PB1-F2-). An asterisk (*) indicates a significant difference (P < 0.00001) compared to both other groups.