Table 1 Hospital non‐survivors: PICU course and clinical data.
| Patient | Admission diagnoses | Co‐diagnoses | Predicted mortality | CDC clinical category | CDC immune category | Nosocomial sepsis (PICU) | Antimicrobial therapy | Ventilatory support (days) | HFOV (days) |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Pneumonia (PJP, Candida albicans) | 0.26 | C | III | Enterobacter cloacae, Klebsiella pneumoniae (pulmonary) | Piptazobactam, amikacin, meropenem, CTX, fluconazole | 18 | 8 | |
| 2 | Pneumonia (PJP, CMV, suspected TB) | Pneumothorax | 0.13 | C | N/D | Suspected | Piptazobactam, amikacin, meropenem, CTX | 13 | 3 |
| 3 | Meningitis (Streptococcal pneumoniae) | Chronic lung disease, pulmonary hypertension | 0.33 | C | N/D | Nil | Cefotaxime | 1 | 0 |
| 4 | Pneumonia (PJP, suspected CMV) | 0.17 | C | N/D | Nil | Piptazobactam, amikacin, CTX | 11 | 4 | |
| 5 | Pneumonia (Candida albicans) | 0.66 | B | N/D | Burkholderia cepacia (pulmonary) | Piptazobacatm, amikacin, meropenem, CTX, amphotericin B | 10 | 10 | |
| 6 | Pneumonia (adenovirus, RSV, suspected CMV, suspected TB) | Septicaemia (Staphylococcus aureus, Alcaligenes dentrificans) | 0.34 | B | N/D | Nil | Ciprofloxacin, vancomycin, meropenem, CTX, fluconazole, anti‐TB agents | 9 | 0 |
| 7 | Pneumonia (suspected PJP) | Septicaemia (Candida fomata), peritonitits (Escherichia coli, Enterococcus faecium) | 0.99 | B | N/D | Nil | Meropenem, CTX, amphotericin B | 8 | 6 |
| 8 | Pneumonia (PJP) | 0.66 | C | N/D | Nil | Cefotaxime, CTX, fluconazole | 11 | 0 | |
| 9 | Pneumonia (PJP, CMV, Escherichia coli) | 0.50 | C | N/D | Nil | Cefotaxime, piptazobactam, amikacin, CTX | 9 | 3 | |
| 10 | Pneumonia (PJP, CMV, Klebsiella pneumoniae) | 0.51 | C | N/D | Nil | Ampicillin, gentamicin, CTX, fluconazole | 4 | 3 | |
| 11 | Dilated cardiomyopathy | 0.22 | B | N/D | Nil | Nil | 0 | 0 | |
| 12 | Pneumonia (RSV, Candida albicans, suspected CMV) | Severe failure to thrive | 0.25 | C | N/D | Suspected (pulmonary) | Piptazobactam, amikacin, fluconazole | 7 | 7 |
| 13 | Pneumonia (PJP) | Neck abscess (Staphylococcus aureus) | 0.42 | C | N/D | Klebsiella pneumoniae/Enterobacter cloacae (pulmonary) | Piptazobactam, amikacin, imipenem, CTX, cloxacillin | 11 | 6 |
| 14 | Pneumonia (suspected PJP) | Tracheostomy | 0.76 | B | N/D | Nil | Ampicillin, gentamicin, CTX | <1 | 0 |
| 15 | Atypical LTB, pneumonia | 0.08 | C | N/D | Nil | Nil | 0 | 0 | |
| 16 | Pneumonia (Suspected PJP, Klebsiella pneumoniae) | 0.90 | B | N/D | Nil | Ampicillin, gentamicin, piptazobactam, amikacin, CTX | 2 | 1 | |
| 17 | Septic shock, gastroenteritis | 0.75 | B | N/D | M/R | M/R | M/R | M/R | |
| 18 | Staphylococcal sepsis (MRSA) | Pneumonia, gastroenteritis | 0.47 | B | I | Nil | Piptazobactam, amikacin, vancomycin, ciprofloxacin, CTX | 6 | 0 |
| 19 | Staphylococcal sepsis (MRSA), suspected PJP | Gastroenteritis (Salmonella Group C), renal impairment | 0.49 | B | III | Nil | Piptazobactam, amikacin, CTX vancomycin, ciprofloxacin | 5 | 2 |
| 20 | Pneumonia | Reye's syndrome, hypoxic brain injury | 0.37 | B | N/D | Nil | Cefotaxime, CTX, acyclovir, fluconazole | 12 | 0 |
| 21 | Pneumonia (Candida albicans, suspected TB) | ARF UTI (Escherichia coli), cardiomyopathy, gastroenteritis | 0.42 | B | I | Nil | Cefotaxime, CTX, fluconazole, anti‐TB agents | 5 | 0 |
| 22 | Pneumonia (PJP, RSV) | Septicaemia (Acinetobacter baumannii) | 0.35 | B | N/D | Nil | Piptazobactam, amikacin, CTX, fluconazole | 18 | 9 |
| 23 | Pneumonia (PJP, Klebsiella pneumoniae, CMV) | 0.78 | C | N/D | Suspected | Ampicillin, gentamicin, piptazobactam, amikacin, CTX, ganciclovir, fluconazole | 5 | 0 | |
| 24 | Pneumonia (PJP) | 0.76 | C | N/D | Suspected | Piptazobactam, amikacin, CTX, meropenem, fluconazole | 12 | 9 | |
| 25 | Pneumonia (PJP, Candida albicans) | 0.29 | C | N/D | Pseudomonas aeruginosa (pulmonary) | Cefuroxime, gentamicin, piptazobactam, amikacin, CTX | 14 | 0 | |
| 26 | Pneumonia (PJP, CMV) | 0.25 | C | N/D | Nil | Ampicillin, gentamicin, CTX | 1 | 0 | |
| 27 | Pneumonia (PJP, Escherichia coli) | 0.24 | C | III | M/R | M/R | M/R | M/R | |
| 28 | Pneumonia (PJP, CMV) | Septicaemia (Klebsiella pneumoniae, Pseudomnas aeruginosa), suspected meningitis | 0.47 | C | III | Nil | Cefotaxime, CTX, fluconazole, anti‐TB agents | 3 | 0 |
| 29 | Pneumonia (PJP, CMV) | 0.12 | C | III | Nil | Piptazobactam, amikacin, CTX | 2 | 0 | |
| 30 | Pneumonia (PJP, CMV, Klebsiella pneumoniae) | 0.42 | C | N/D | Nil | Piptazobactam, amikacin, CTX, fluconazole | 5 | 0 | |
| 31 | Pneumonia (Suspected PJP, Klebsiella pneumoniae) | Gastroenteritis | 0.26 | B | N/D | Nil | Piptazobactam, amikacin, CTX | 4 | 3 |
| 32 | Pneumonia (PJP, CMV, Candida albicans) | 0.69 | C | N/D | Nil | Ampicillin, gentamicin, CTX, fluconazole | 2 | 0 | |
| 33 | Pneumonia (PJP, CMV, Enterobacter cloacae) | 0.57 | C | III | Nil | Ampicillin, gentamicin, piptazobactam, amikacin, CTX, ganciclovir | 5 | 4 |
CMV, cytomegalovirus; CTX, cotrimoxazole; LTB, laryngotracheobronchitis; M/R, missing record; N/D, not done; PJP, pneumocystis jirovecii pneumonia; RSV, respiratory syncytial virus; TB, tuberculosis.