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. Author manuscript; available in PMC: 2007 Nov 21.
Published in final edited form as: J Pharm Biomed Anal. 2007 Aug 2;45(2):295–303. doi: 10.1016/j.jpba.2007.07.026

Figure 1.

Figure 1

The N-dechloroethylation of (R)- and (S)-ifosfamide by cytochrome P450 enzymes (CYP 3A4 and CYP 2B6) to yield the 2-N-dechloroethyl (2-DCE-IFF) and 3-N-dechloroethyl (3-DCE-IFF) metabolites. Reprinted with permission from [11].