Table 3 Protocol for cardiovascular assessment of Marfan's syndrome.

Clinical assessment	Comment
Weight/height	Allows calculation of body surface area for aortic root nomogram
Auscultation	Ejection click is common if aortic root dilated, mid‐systolic click may be present in valve prolapse. Murmurs usually associated with valve regurgitation
Blood pressure	If on β‐blocker, calcium antagonist or ACE inhibitor/receptor blocker
Electrocardiogram	12‐lead ECG at each visit. Consider ambulatory or event monitor if palpitations
Echocardiogram	Full study every 6–12 months during childhood. Measure LV dimensions and function, pulmonary valve diameter, aortic root diameter. Plot aortic root against body surface area nomogram.

ACE, angiotensin‐converting enzyme; ECG electrocardiography; LV, left ventricular.