Table 1 Descriptive data of the patients at the start of treatment and at the latest recording, and untreated controls age matched to the patient's age at the latest recording.
| Patientno | OI type | Sex | Age (years) at start | Height/weight at start, SD | Age (years) latest record | Height/weight latest record, SD |
|---|---|---|---|---|---|---|
| 1 | IV | F | 1.1 | −6.5/−6.1 | 6.1 | −4.0/−2.7 |
| 2 | IV | F | 1.1 | −6.0/−5.3 | 6.2 | −4.8/−2.8 |
| 3 | IV | M | 0.5 | −11.0/−5.5 | 6.5 | −7.2/−3.8 |
| 4 | III | M | 0.4 | −11.5/−2.5 | 6.4 | −5.0/−3.7 |
| 5 | I | M | 0.25 | −0.6/0.2 | 5.8 | −3.2/−2.1 |
| 6 | I | M | 0.3 | 0.5/0.6 | 4.3 | −3.0/−0.6 |
| 7 | IV | F | 0.3 | −2.0/1.0 | 3.3 | −3.0/−1.0 |
| 8 | III | M | 0.24 | −7.0/−3.6 | 4.8 | −7.0/−5.0 |
| 9 | III | F | 0.3 | −1.2/−1.3 | 3.3 | −3.2/−2.5 |
| 10 | III | F | 0.3 | −5.5/−6.0 | 3.3 | −5.5/−4.1 |
| 11 | III | F | 0.25 | −0.8/−2.0 | 3.3 | −5.0/−3.2 |
| Mean | 0.5 | −4.7/−2.8 | 4.8 | −4.6/−2.9 | ||
| Median | 0.3 | −5.5/−2.5 | 4.8 | −4.8/−2.8 |
| Controlno | OI type | Sex | Age (years) at early record | Height/weight at early record, SD | Age (years) before treatment | Height/weight before treatment, SD |
|---|---|---|---|---|---|---|
| c 4 | III | M | 1.5 | −9.0/−3.5 | 2.7 | −9.5/−3.0 |
| c 5 | III | M | 0.7 | −9.5/−3.8 | 3.1 | −9.0/−3.5 |
| c 6 | I | M | 0.25 | −2.0/−2.2 | 3.7 | −4.0/−2.5 |
| c 7 | IV | F | 1.2 | −4.6/−3.1 | 3.9 | −5.0/−3.5 |
| c 8 | III | F | 0.75 | −3.5/−3.0 | 3.9 | −5.0/−2.5 |
| c 9 | IV | F | * | * | 4.6 | −2.7/−2.4 |
| c 10 | IV | M | 0.25 | −2.0/−1.0 | 6.4 | −3.2/−0.5 |
| c 11 | III | F | 0.7 | −9.3/−6.0 | 7.0 | −12.0/−5.8 |
| c 12 | I | F | * | * | 7.3 | −4.5/−1.3 |
| c 13 | IV | F | 0.5 | −2.8/−3.3 | 8.6 | −8.7/−5.0 |
| c 14 | I | M | 0.25 | −6.0/−5.2 | 9.0 | −3.7/0.3 |
| Mean | 0.7 | −5.4/−3.5 | 5.5 | −6.1/−2.7 | ||
| Median | 0.7 | −4.6/−3.3 | 4.6 | −5.0/−2.5 |
f, female; m, male; OI osteogenesis imperfecta.
The SD scores are age‐adjusted.
*No early data available.