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. 2007 May;92(5):426–433. doi: 10.1136/adc.2006.095760

Table 3 Vaccines available (or expected to be available within 5 years) to broaden protection of children against infectious diseases.

Vaccine Availability Target age group Use Additional information
Universal hepatitis B Now As a combination or stand‐ Prevention of hepatitis B High efficacy. Used in most developed
vaccine alone vaccine for infants or transmission countries. Recommended by the WHO
pre‐adolescents
Boosters of acellular Now As a teenage booster To reduce disease and transmission Recommended in the USA
pertussis vaccine vaccine of pertussis among young adults and
from young parents to their infants
Varicella vaccine Now Combined with MMR or as Reduction of morbidity and mortality Universal immunisation in the USA
a separate vaccine in associated with varicella and and Canada
toddlers, or as a catch‐ complications of varicella (especially
up for adolescents bacterial superinfection)
Hepatitis A vaccine Now Children over 12 months Control of endemic and epidemic Used in Israel and recently added to the
of age hepatitis A and as a travel vaccine USA immunisation schedule in response
to outbreaks of hepatitis A
Influenza vaccine Now Highest disease rates in the Reduction of influenza morbidity Universal immunisation recommended
those under 2 years of age and mortality in early childhood in the USA
Higher valency Expected within Infant immunisation but has Prevention of bacteraemia, Coverage of serotypes not included in
pneumococcal several years potential benefit for older pneumonia and meningitis and PnC7 that cause significant burden of
conjugate vaccines children and adults reduction of death and disability disease, such as serotype 1. Efficacy
(PnC10 and PnC13) caused by Streptococcus pneumoniae data not available
Rotavirus vaccine Available since Infants under 6 months Prevention of rotavirus morbidity, High efficacy against severe disease
mid‐2006 of age hospitalisation and mortality and hospitalisation. Introduced in
(estimated 14 deaths per year in the Mexico and available on private
UK) prescription in Europe
Human papilloma Available now Pre‐adolescent girls? Prevention of cervical cancer High efficacy reported
virus vaccines in some regions and genital warts
Meningococcal One vaccine As a toddler vaccine for direct Broader protection against Introduced for teenagers in the USA
ACYW available now protection of children or a meningococcal infection and Canada
vaccines and and others in teenage vaccine to provide
other various the pipeline direct protection in this at‐risk
combinations age group and herd immunity