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. Author manuscript; available in PMC: 2008 Sep 21.
Published in final edited form as: Neuroscience. 2007 Jul 17;148(4):978–995. doi: 10.1016/j.neuroscience.2007.07.013

Fig. 4.

Fig. 4

Changes in discharge rate (mean±standard error, imp/0.5 s) induced by tail-touch and tail-pinch in rats in rats during urethane anesthesia and in awake conditions with DA receptor blockade. In awake conditions, each stimulus had a significant, strong effect on discharge rate (touch: F32,1022=7.31, pinch: F 20,650=6.52; p<0.001 for each case). During anesthesia, the effect of time was also significant in each case but quite different in its strength (touch: F40,819=1.61, p=0.043, pinch: F51,1091=6.60; p<0.001). Filled symbols show values significantly higher (Fisher F test) than baseline. Because discharge rate increased immediately preceding stimulus onset, mean basal rate was calculated based on 5-s before stimulus presentation (shown as a hatched horizontal line). n is the number of tested units.