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. Author manuscript; available in PMC: 2008 Oct 12.
Published in final edited form as: Biochem Biophys Res Commun. 2007 Jun 18;362(1):5–10. doi: 10.1016/j.bbrc.2007.06.050
Tumor staging
 Grade I: 3–5 points
 Grade II: 6–7 points
 Grade III: 8–9 points
Tubule formation:
 More than 75% of the tumor 1
 From 10–75% of the tumor 2
 Less than 10% of the tumor 3
Nuclear pleomorphism:
 Small and regular nuclei 1
 Moderate increase in nuclear size 2
 Marked pleomorphism or nucleolus 3
Mitotic index:
 0–8 mitosis per 10 fields 1
 9–16 mitosis per 10 fields 2
 More than 17 mitosis per field 3