(a) Far-UV CD spectrum of Con-T at 25°C. (b) Mean residue ellipticity of Con-T at 222 nm as a function of temperature. Open circles correspond to peptide samples of low ionic strength (i.e., in 20 mM phosphate buffer, pH 7), whereas open triangles represent a peptide sample of high ionic strength (i.e., in 20 mM phosphate buffer, pH 7, and 2.0 M NaCl).