Table 2.

Baseline levels and changes over 6-month follow-up in cardiovascular biomarkers among TEA Pilot Study participants.

	Tea (n=14)			Water (n=14)
	Baseline	6-months	Difference	Baseline	6-months	Difference	P-value
HDL-C (mg/dl)	62 ±3	62 ±2	−0.5 ±2.0	64 ±4	64 ±5	+0.1 ±3.4	0.87
Triglycerides (mg/dl)	148 ±24	116 ±13	−32 ±19	160 ±46	125 ±20	−35 ±28	0.65
LDL-C (mg/dl)	111 ±12	98 ±9	−13 ±10	116 ±8	119 ±9	+2 ±5	0.32
Glucose (mg/dl)	92 ±4	99 ±6	+7 ±4	102 ±14	103 ±9	+1 ±6	0.91
WBC (K/μl)	6.3 ±0.4	5.8 ±0.3	−0.5 ±0.2	7.3 ±0.4	7.0 ±0.4	−0.2 ±0.4	0.25
Hemoglobin (g/dl)	13.5 ±0.3	13.4 ±0.3	−0.1 ±0.3	13.5 ±0.3	13.5 ±0.3	+0.1 ±0.2	0.59
Albumin (g/dl)	4.31 ±0.08	4.36 ±0.06	+0.05 ±0.07	4.26 ±0.07	4.41 ±0.06	+0.15 ±0.06	0.29
Homocysteine (μmol/L)	8.4 ±0.4	8.7 ±0.4	+0.3 ±0.2	9.9 ±0.5	9.7 ±0.6	−0.1 ±0.5	0.31
Fibrinogen (mg/dl)	330 ±19	319 ±25	−11 ±23	379 ±27	391 ±22	+12 ±29	0.52
Factor VIII (%)	134 ±10	135 ±9	+3 ±7	161 ±13	152 ±10	−9 ±9	0.31
CRP (mg/dl)	0.13 ±0.03	0.14 ±0.03	+0.01 ±0.02	0.79 ±0.27	0.67 ±0.16	−0.12 ±0.28	0.50
IL-6 (pg/ml)	1.6 ±0.2	1.5 ±0.1	−0.2 ±0.3	2.0 ±0.3	2.2 ±0.3	+0.2 ±0.4	0.35
TNF-α (pg/ml)	1.9 ±0.2	2.3 ±0.2	+0.4 ±0.2	2.0 ±0.3	2.4 ±0.3	+0.5 ±0.2	0.86
sICAM (ng/ml)	238 ±13	235 ±16	−3 ±11	276 ±19	268 ±16	−8 ±8	0.72
sVCAM (ng/ml)	703 ±58	819 ±96	+116 ±57	719 ±58	764 ±68	+53 ±26	0.42
vWF (%)	140 ±13	136 ±9	−4 ±7	158 ±14	165 ±15	+7 ±7	0.28
tPA-antigen (ng/ml)	8.9 ±0.6	8.1 ±1.0	−0.8 ±0.7	10.5 ±1.1	10.1 ±0.9	−0.4 ±0.7	0.69
PAI-1-activity (U/ml)	15 ±5	24 ±5	+9 ±5	18 ±4	23 ±7	+5 ±4	0.60
Lag time (seconds)	76 ±11	85 ±11	+9 ±19	96 ±8	80 ±7	−16 ±10	0.31

P-values derived from t-tests or Wilcoxon rank sum tests comparing baseline-to-6-month differences among participants assigned to tea versus water.

Single outlying values deleted for baseline CRP and sICAM.