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Influence of polyP on mitochondrial function. Cells with no identifiable green fluorescence were used as controls. (a) Reduction of mitochondrial inner membrane potential associated with reduced polyP levels. HepG2 expressing MGP showed lower TMRM fluorescence than controls. **, p < 0.001. (b) Increase of the basal level of NADH autofluorescence in cells expressing MGP. Values of fluorescence in the presence of FCCP (1 μM), or NaCN (1 mM), were taken as 0% and 100%, respectively.
