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Adrenal gene expression in MC2R KO mice. Expression of Cyp11a1 (A), Cyp21a1 (B), Cyp11b1 (C), Cyp11b2 (D), AT1bR (E), TH (F), Phox2a (G), and phenylethanolamine N-methyltransferase (PNMT) (H) in adrenal glands from female 12-wk-old MC2R−/− (n = 4) and MC2R+/+ (n = 3) mice was determined by qRT-PCR. Data are expressed as means ± SEM. Statistical significance was determined by t test. ###, P < 0.001; ##, P < 0.01; #, P < 0.05.
