Table 1.
Genotypes |
No. of blastocysts transferred | No. of recipients | No. of mice with IS (%) | No. of IS (%) | No. of blastocysts recovered from mice without IS (%) | |
---|---|---|---|---|---|---|
Blastocysts | Recipients | |||||
+/+ | +/+ | 2143 | 9 | 8 (89) | 66 (46) | 0 (0) |
+/+ | −/− | 156 | 8 | 2 (25) | 19 (12) | 19 (12) |
−/− | +/+ | 83 | 8 | 7 (88) | 36 (43) | 2 (2) |
Day 4 WT (+/+) or Hbegf null (−/−) blastocysts were transferred into WT or mutant pseudopregnant recipients on day 4 midmorning, and implantation was examined 24 h later by the blue dye method.