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. Author manuscript; available in PMC: 2007 Nov 21.
Published in final edited form as: Cell. 2007 Jun 29;129(7):1311–1323. doi: 10.1016/j.cell.2007.05.022

Figure 6. HOTAIR is required for H3K27 trimethylation and Suz12 occupancy of the HOXD locus.

Figure 6

(A) Change in H3K27me3 ChIP-chip signal over the HOXD locus caused by depletion of HOTAIR compared to control siRNA against GFP. The location of HOXD genes are indicated by brown boxes.

(B) ChIP of H3K27me3 and Suz12 of select promoters across the HOXD locus after siRNA treatment targeting GFP or HOTAIR. Bottom: quantitation of ChIP assays (mean ± standard error).