Suppression of SNL-induced neuropathic pain by a neutralizing antibody against CX3CR1. A single injection of a neutralizing CX3CR1 antibody (10 μg, 20 μl) into lumbar CSF space, 30 min before surgery, decreases SNL-induced mechanical allodynia on post-surgery day 1 and day 2. Control serum (10 μg) has no effect. **, P<0.01, compared to corresponding serum control, unpaired t-test, n=6.