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. Author manuscript; available in PMC: 2007 Nov 21.
Published in final edited form as: Brain Behav Immun. 2006 Dec 15;21(5):642–651. doi: 10.1016/j.bbi.2006.11.003

Figure 8.

Figure 8

Fractalkine does not produce acute effect on synaptic transmission in the spinal cord. (a) Patch clamp recording in lamina II neurons of the isolated spinal cord slices shows spontaneous excitatory synaptic current (sEPSC) before, during, and after bath application of fractalkine (20 ng/ml, 5 min). (b, c) High magnification shows sEPSC before (a) and after (b) fractalkine (20 ng/ml) application. (d, e) Effects of fractalkine on the frequency (d) and amplitude (e) of mEPSC. Data are presented as the ratio of pre-treatment value. P>0.05, paired t-test, n=3.