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. Author manuscript; available in PMC: 2007 Nov 21.
Published in final edited form as: Endocrinology. 2007 Mar 1;148(6):2669–2680. doi: 10.1210/en.2006-1587

Figure 5.

Figure 5

Measurement of the RANKL and OPG mRNA expression in bone as a function of age and rosiglitazone administration. Total RNA was extracted from the proximal tibia and analyzed by real time PCR. (A) Determination of the RANKL/OPG mRNA ratio. (B) RANKL mRNA expression levels. (C) OPG mRNA expression levels. Tibiae RNA were extracted from the following number of animals in each group: young - 4 control and 4 rosiglitazone, adult – 3 control and 4 rosiglitazone, old – 4 control and 4 rosiglitazone. Gray bars – control; black bars – rosiglitazone. * p < 0.05 vs. control; # p < 0.05 vs. young animals; ^ p < 0.05 vs. adult animals.