Table V.
Number of non-Hodgkin lymphoma cases and controls and odds ratios according to NAT2 phenotype and permanent hair coloring product use before 1980, by color, tone, frequency, duration, and total lifetime applications (women only).
| NAT2 slow | NAT2 rapid/intermediate | |||||
|---|---|---|---|---|---|---|
| Hair coloring product use | Cases | Controls | ORa (95% CI) | Cases | Controls | ORa (95% CI) |
| No hair dye < 1980 | 37 | 38 | 1.0 (referent) | 32 | 41 | 1.0 (referent) |
| Any hair dye < 1980 | 139 | 109 | 1.3 (0.7,2.2) | 103 | 73 | 1.9 (1.0,3.4) |
| Permanent dye (any) | 68 | 48 | 1.3 (0.7,2.4) | 58 | 37 | 2.0 (1.0,4.0) |
| Permanent, dark colors (black, brown, red) | 45 | 26 | 1.6 (0.8,3.2) | 36 | 25 | 2.2 (0.98,4.9) |
| Permanent, intense tones (black, dark brown, dark blonde) | 23 | 14 | 1.5 (0.6,3.6) | 25 | 11 | 3.3 (1.3,8.6) |
| Frequency (number of applications/year) | ||||||
| 1-4 | 8 | 1 | - | 7 | 5 | 2.3 (0.6,8.9) |
| ≥ 5 | 15 | 13 | 0.9 (0.3,2.5) | 18 | 6 | 4.2 (1.3,13.2) |
| Duration (years) | ||||||
| 1-4 | 14 | 8 | 1.6 (0.6,4.7) | 11 | 7 | 2.4 (0.8,7.3) |
| ≥ 5 | 9 | 6 | 1.3 (0.4,4.5) | 14 | 4 | 5.4 (1.4,21.1) |
| Cumulative applications | ||||||
| 1-24 | 14 | 6 | 2.1 (0.7,6.6) | 9 | 6 | 2.3 (0.7,7.9) |
| ≥ 25 | 9 | 8 | 1.0 (0.3,3.1) | 16 | 5 | 4.6 (1.4,15.7) |
a
Odds ratio (95% CI), adjusted for age, race, and SEER area.
-
Odds ratio not calculated if observed less than 2.