Table 1.
Baseline characteristics of PHS and WHS study participants who subsequently developed CVD (Cases), and those who remained free of vascular disease during follow-up (controls). All participants were white men (PHS) or women (WHS).
| Male Controls | Male CVD Cases | P | Female Controls | Female CVD Cases | P | |
|---|---|---|---|---|---|---|
| (N=566) | (N=566) | (n=296 | (n=296) | |||
| Age (years) | 60.7±0.4 | 61.0±0.4 | m.v.* | 63.6±0.4 | 63.7±0.4 | m.v.* |
| Smoking Status (%) | ||||||
| Never | 42.2 | 42.2 | m.v | 40.5 | 40.5 | m.v. |
| Past | 41.5 | 41.5 | 41.2 | 41.2 | ||
| Current | 16.3 | 16.3 | 18.2 | 18.2 | ||
| Hormones Use (%) – women only | ||||||
| Never | -- | -- | 34.5 | 34.5 | m.v. | |
| Past | -- | -- | 22.3 | 22.3 | ||
| Current | -- | -- | 43.2 | 43.2 | ||
| Body Mass Index (kg/m2) | 24.8±0.1 | 25.4±0.1 | 0.002 | 25.6±0.3 | 27.0±0.3 | 0.001 |
| Hyperlipidemia† | 15.3 | 22.7 | 0.002 | 50.2 | 58.2 | 0.07 |
| Hypertension (%)‡ | 37.9 | 46.5 | <0.0001 | 33.7 | 54.2 | <0.0001 |
| Diabetes (%) | 2.8 | 8.9 | <0.0001 | 4.0 | 12.0 | <0.001 |
| Parental history of premature CAD (%)§ | 8.9 | 11.6 | 0.14 | 9.9 | 17.0 | 0.03 |
| Aspirin use (%) | 47.4 | 45.2 | 0.49 | 50.7 | 44.6 | 0.14 |
Mean±SE unless otherwise stated.
*
m.v., matching variable.
†
Hyperlipidemia defined as self-report of history of total cholesterol >240mg/dL).
‡
Hypertension defined as physician diagnosis of hypertension or reported BP of >140 mmHg systolic or >90 mmHg diastolic blood pressure.