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Small colony formation by yeast transformed with pAD–BRCA1. (A) Photograph of S. cerevesiae HF7c colonies after transformation with the indicated plasmids. pAD, pACT2 control vector; pAD–BRCA1, BRCA1 in pACT2; pAD–TAg, simian virus 40 large T antigen in pACT2. (B) Yeast growth curves in YPD media. Each point represents a mean of three cultures ± SEM.
