Fig. 3.

Antithrombin is active in plasma fibronectin-deficient mice but is inactive in vitronectin-null mice. Mice with matrigel plugs were treated with seven daily i.p. injections of 270 μgor180 μg of antithrombin (antithr) or PBS, as in Fig. 2. The number of blood vessels in the plugs is shown. Results from mice treated with the two doses were pooled (16 mice in fibronectin experiments; 24 mice in vitronectin experiments).