Table 2. Rearrangement statistics of the mouse genome relative to human.
Genomewide frequency (events per megabase) | Finished frequency (events per megabase) | Genome median size | Finished median size | |
---|---|---|---|---|
Inversion | 2.0 | 1.8 | 814 | 762 |
Inversion + local duplication | 0.5 | 1.0 | 275 | 302 |
Inversion + local part duplication | 0.7 | 0.8 | 517 | 1235 |
Local move | 0.8 | 1.0 | 204 | 246 |
Local duplication | 1.9 | 4.0 | 211 | 351 |
Local part duplication | 0.9 | 1.2 | 343 | 388 |
Syntenic move | 0.8 | 1.6 | 223 | 322 |
Syntenic duplication | 1.3 | 1.2 | 283 | 286 |
Syntenic part duplication | 0.7 | 0.8 | 474 | 946 |
Nonsyntenic move | 5.0 | 5.2 | 104 | 109 |
Nonsyntenic duplication | 11.9 | 11.6 | 235 | 228 |
Nonsyntenic part duplication | 4.6 | 4.6 | 282 | 256 |
Mouse 1 base gaps | 1,461.8 | 1,513.4 | 1 | 1 |
Mouse 10 base gaps | 39.7 | 46.4 | 10 | 10 |
Mouse gaps ≥ 100 | 68.8 | 80.8 | 207 | 201 |
Double gaps ≥ 100 | 398.6 | 419.9 | 444 | 411 |
H likely deletion ≥ 100 | 230.0 | 223.5 | 685 | 633 |
The finished columns show rearrangements within the 96.3 megabases of mouse sequence that were finished in this assembly. The genome columns refer to the entire 2.47-gigabase mouse assembly. A move or inversion involves no duplicated sequence. “Duplication” means at least 80% of the aligning bases of the rearranged chain align to multiple places in the human genome. “Part duplication” means some sequence, but <80% is duplicated. The moves and duplications of <100,000 bases are considered local. Syntenic moves and duplications are on the same chromosome but >100,000 bases away and may be inverted as well. Nonsyntenic moves and duplications fill gaps in a chain with sequence from another chromosome. The “single gaps ≥100” row shows gaps of 100 or more bases in mouse and 0 bases in human. The “double gaps ≥ 100” row shows gaps of 100 or more in mouse and >0 bases in human. The “h likely deletion ≥100” row counts gaps in the mouse genome that are not the result of human lineage-specific transposons or Ns, and that are at least 100 bases.