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Enhancer and silencer activities of NRSE within synthetic promoters. (a) Schematic representation of the plasmids used for transfection. Oval, three NRSEs; crossed-out oval, mutated NRSEs; solid box, SV40 TATA box; hatched box, myosin IIB TATA box. (b) Relative activity of these plasmids transfected in different cell lines. The luciferase activities were normalized to that of the same plasmid containing no NRSE sequences (SVP-Luci, TATA-Luci, or TATAIIB-Luci).
